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Does Coffee Cause Cancer?

Coffee and craft-beer continue to be the prominent beverages of choice amongst cyclists these days, with the average hipster pedal-pusher seemingly consuming them by the tankard on a daily basis.

We all know that drinking beer in large quantities can lead to significant weight-grain, particularly outside of regular exercise, which raises a whole host of other health concerns. But, does the presence of acrylamide in coffee raise even greater health concerns for cyclists who routinely consume the little brown bean is staggering amounts each day?

The legal system in California seems to think so. 

Indeed, a California judge recently ruled that Starbucks and other coffee companies in the state must serve the drink with a cancer warning. The legal issue comes from the presence of acrylamide in coffee. This chemical is typically found in many foods with a high carbohydrate content that are exposed to high temperatures, including cakes, potato chips, bread and cereals. Evidence shows that acrylamide is probably a human carcinogen, a cancer-causing substance.

The acrylamide in coffee is formed early in the roasting process, which turns the fresh green beans the dark brown color we are familiar with and gives coffee its deep bitter flavour. Once inside the body, acrylamide can be converted to another compound, epoxide glycidamide, and both of these chemicals can bind to and damage our proteins and DNA. Damage to DNA can be the first step in the development of cancer, and acrylamide also interferes with DNA repair.

The problem with the recent court ruling was that person bringing the case only needed to show there were trace amounts of acrylamide in coffee in order to succeed. This is where the reality of our lifestyles makes the ruling seem over-cautious.

Nobody disputes that coffee contains acrylamide or that acrylamide causes DNA damage, but it’s how much you consume that is important. The risk is really related to the total sum of exposure over a lifetime, but one estimate suggests an 175 pound adult consuming more than 7 ounces of acrylamide a day should not have any increased risk of cancer.

The main lifestyle choice that exposes people to toxins is smoking. Each cigarette contains around half an ounce of acrylamide, among a cocktail of other carcinogens. But all the foods we roast or fry to get delicious caramelisation also contain acrylamide. So non-smokers’ lifestyles are not acrylamide-free, with 2 ounces in a slice of toast or 2.5 ounces in a bag of potato crisps, as examples.

A cup of coffee fits into our daily acrylamide exposure at around half an ounce to an ounce grams per 8 ounce cup. But every cup also contains a diverse array of anti-oxidants and other compounds thought to have positive health effects (outside of pregnancy).

The same group of scientists (working for the World Health Organization), who classified acrylamide as probably carcinogenic, found there was no conclusive evidence that drinking coffee caused cancer. In fact, they suggested coffee drinking may protect against liver and endometrial cancers and more recent studies have supported this idea. In 2016, the WHO took coffee off its list of possible carcinogens.

Scientists’ original concern over coffee drinking followed studies that suggested a possible link with bladder cancer. But closer analysis of the data and larger scale studies showed that the original research was confused by not taking account of smoking habits. It’s possible that coffee drinking interacts with smoke carcinogens to increase the risk of bladder cancer for smokers. In non-smokers, there is no robust evidence of a link between coffee and bladder cancer.

If you’re still worried about the acrylamide in coffee, it’s worth noting that less acrylamide seems to make it into the cup when the coffee is filtered than made using the espresso method. The choice of beans and roasting time might be important too since Robusta contains more acrylamide than Arabica, and darker roasts contain less than lighter ones.

Verdict

Acrylamide isn’t good for you but the amount present in coffee makes no observable contribution to cancer risk. There is no strong evidence for a link between drinking coffee and developing cancer. While there have been occasional studies suggesting an increased risk in bladder cancer, overall the vast majority of rigorous studies suggest that if coffee drinking has any effect at all it actually offers a mild protective effect from some cancer types.

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